Weight watching in cardiology: low molecular weight heparin for acute coronary syndromes
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چکیده
منابع مشابه
Weight watching in cardiology: low molecular weight heparin for acute coronary syndromes.
Heparin is available for clinical use since the 1950’s and has over the last years firmly established its role as the anticoagulant agent of choice in the prevention and treatment of venous thromboembolism as well as in the manw x agement of acute coronary syndromes 1 . Heparin anticoagulation, however, has limitations, partly due to the unpredictable bioavailability of the compound and its lar...
متن کاملLow molecular weight heparins versus unfractionated heparin for acute coronary syndromes.
BACKGROUND Acute coronary syndromes (ACS) are an important source of morbidity and mortality. Despite weak evidence for the use of unfractionated heparin (UFH) for acute coronary syndromes it is considered an accepted treatment for unstable angina and non-ST segment elevation myocardial infarction (MI). However, evidence suggests low molecular weight heparins (LMWH) are safer and more effective...
متن کاملLow-molecular-weight heparins in acute coronary syndromes.
Platelet aggregation, and activation of coagulation cascade are the key events in the development of acute coronary syndromes (ACS). Patients with this syndrome are at high risk of adverse events, such as death and myocardial infarction (MI). Optimized medical treatment for the non-ST segment elevation ACSs should consist of a combined anti-thrombotic/anti-anginal regimen. Standard anti-thrombo...
متن کاملReview: low-molecular-weight heparin is effective and safe in the acute coronary syndromes.
D a t a e x t r a c t i o n Data were extracted on methods, participant numbers, interventions, and outcomes. M a i n r e s u l t s 4 large RCTs compared LMWH with UFH in UA/NSTEMI; 2 of these RCTs (7081 patients) showed that enoxaparin was more effective than UFH at 14 days for the combined endpoint of death, MI, and recurrent ischemia with or without revascularization. For the initial medical...
متن کاملHeparin Rebound Phenomenon in Acute Coronary Syndromes: Advantage of Low Molecular Weight Heparins
Heparin rebound phenomenon was named to illustrate unstable angina pectoris (UAP) reactivation after stopping heparin. Reinfarction clustering, as well as sharp increase of both thrombin production and activity in the early hours after heparin abandoning have been described (after thrombolysis), which has been partially attributed to heparin rebound. The aim of the study was to show importance ...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 1998
ISSN: 0008-6363
DOI: 10.1016/s0008-6363(97)00303-9